As panties are a daily necessity for most of us, comfort is key, as is durability. Your go-to undies are going to be seeing a lot of wash cycles, and if they’re not made of decent quality, they’re going to start to fray or lose their elasticity, and therefore, their level of comfort. So look for cotton panties for women that explicitly states they are machine washable, or try and get in the habit of hand washing your most delicate pairs. Another reason for underwear that causes discomfort for women is the fabric itself. Cotton is generally the most breathable and moisture-absorbent option.